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Institute specific line designations should be two or three letters in length, preferably two letters. These designations should not be the same as a gene name in mouse or human. The institution designation should be followed by a unique number specific to a particular line. Other letters should not immediately follow the institution designation but may be appended to the end of the line designation to make it unique. Line designations should only contain alphanumeric characters. Dominant and Semi-dominant alleles have a d in the first position of the line designation to distinguish them from recessive alleles. Semi-dominant is defined as the situation when the penetrance phenotype of the mutant phenotype in a mutant-allele/wild-type allele heterozygote is less than complete. For example, only 70% of the individuals show the phenotype rather than 100%. severe than the mutant-allele homozygote. This means that the letter 'd' cannot begin an institution designation. Line designations for transgenic lines follow these same rules, so the same number cannot be give to both a transgenic line and a mutant allele.
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Active Contributors:
Richard Dorsky (richard.dorsky@neuro.utah.edu), Department of Neurobiology and Anatomy, University of Utah, USA
Marc Ekker (mekker@uottawa.ca), Center for Advanced Research in Environmental Genomics, University of Ottawa, Ontario, Canada
Steve Johnson (sjohnson@genetics.wustl.edu), Department of Genetics, Washington University Medical School, USA
Mary Mullins (mullins@mail.med.upenn.edu), Department of Cell and Developmental Biology, University of Pennsylvania, USA
John Postlethwait (jpostle@oregon.uoregon.edu), Institute of Neuroscience, University of Oregon, USA
Monte Westerfield (monte@uoneuro.uoregon.edu), Institute of Neuroscience, University of Oregon, USA
Jeffrey Yoder (Jeff_Yoder@ncsu.edu), Department of Molecular Biomedical Sciences Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, USA
Past Contributors:
Erik Segerdell, XenBase, University of Calgary, Canada
Melissa Haendel (haendel@ohsu.edu)), Oregon Health and Sciences University, USA
Ceri Van Slyke (van_slyke@uoneuro.uoregon.edu), Zebrafish Information Network, University of Oregon, USA
Yvonne Bradford (ybradford@zfin.org), Zebrafish Information Network, University of Oregon, USA
Steve Johnson (sjohnson@genetics.wustl.edu), Department of Genetics, Washington University Medical School, USA
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8. REFERENCES
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For questions and advice about appropriate nomenclature, contact us at nomenclature@zfin.org .