Post doctoral position (2yrs starting 2023/2024)
The impact of environmental contaminants on neuro and cardiovascular development.
The Institute of functional genomics, Montpellier, France
The harmful effects of poisonous high-levels of environmental pollutants and intoxication to the central nervous (CNS) and cardiovascular systems are proven. Surprisingly, insufficient information is available concerning the impact of exposure to bisphenol analogues (BPA/BPS/BPF/BPAF) widely used in industrial processes. Public relevance further grows when considering the effects that bisphenol analogues could have during development, in particular to forming brain and cardio-vascular structures.
We now seek a post-doctoral researcher to test the hypothesis that exposure to bisphenol analogues during development, in compositions and dosages pertinent to environmental contamination, results in neuro- and cardio-vascular defects. The newly hired post-doc will use zebrafish as a model for studying neuro-vascular and cardio-vascular development. In particular the researcher will develop i) a fast and effective in vivo screening of neuro- and cardio-vascular changes induced by bisphenol exposure; ii) spatio-temporal 2-Photon reconstructions of the developing neuro- and cardio-vascular structures exploiting ad hoc transgenic zebrafish; iii) provide support for optical mapping of brain and cardiac structures following bisphenol analogue exposure iv) identify the genetic signature consequent to the exposure to bisphenol analogues during brain and cardiac development.
The ideal candidate will have experience working with zebrafish, and will be familiar with 2 photon microscopy and basic molecular biology.
Deadline for applications- October 31st 2023. Starting end 2023/start 2024
Contacts- Nicola Marchi, Nicola.Marchi@igf.cnrs.fr
Chris Jopling, Chris.Jopling@igf.cnrs.fr