PhD and Postdoc Positions, Mueller Lab, University of Birmingham, Birmingham, United Kingdom

The Mueller lab studies the regulatory principles and DNA sequence determinants of transcription regulation in the developing vertebrate embryo and in cancers. We apply functional genetic analysis, genomics technologies and computational biology tools. We exploit the transparency of the fish embryo in visualising developmental processes and gene expression control. We are located in the Department of Cancer and Genomic Sciences and are members of the Birmingham Centre for Genome Biology . Funding for our work has been received from H2020 programmes of the European Commission, HU-RIZON, BBSRC and the Wellcome Trust. We are seeking candidates for exciting new positions in our dynamically growing group and offer training in - and/or desire experience with: zebrafish gene editing, transgenesis, genomics (bulk and single cell multi-omics).

Research fellow in developmental toxico-genomics

2 years fixed term

This HU-RIZON-funded post is established to study the transcriptomic mechanisms of toxicity by PFAS compounds. The post holder will be part of a multi-disciplinary research team working in an international consortium. The main role will be to apply and develop new methods of genome wide analysis of transcription dynamics on the single cell level in the complexity of zebrafish larvae and will use genomics technologies (single cell ATAC seq, single cell 5’ end transcriptomics) and then analyse the data by cutting edge computational genomics tools to achieve new models of transcription and its regulation upon exposures to PFAS compounds and to answer questions about cell and tissue source of toxicity and dissection of adverse effect pathways. They will develop and perform single cell genomics and apply genomics data analysis tools and will have the opportunity for advanced training in these areas.
Details: https://shorturl.at/UWtUV ;

Deadline for application: 11/11/2025; Informal enquiries: f.mueller@bham.ac.uk

PhD positions

Title: How does the interplay between metabolism control and gene regulation shape embryo development? Competitive, BBSRC MIBTP-funded 4 years project, awarded upon shortlisting for the doctoral training programme (DTP) and upon successful interview by the DTP panel. Available to UK and international candidates (the latter within quota for the DTP programme). Project summary : https://shorturl.at/3zcmP

Application process: https://shorturl.at/RDzd6 .
Deadline of application: 27/11/2025

Informal enquiries: f.mueller@bham.ac.uk

Another PhD position for those interested in working with cancer organoids and transcription initiation control of metabolism and growth (https://shorturl.at/wh6nW)