Blog from December, 2021

Neuroscience- Assistant Professor

The Department of Biological Sciences at the University of North Texas (UNT), a Hispanic-Serving Institution and a Carnegie Research Tier 1 institution, invites applicants for a tenure-track Assistant Professor position with a research focus in Neurobiology. This includes (but is not limited to) research in neural development, diseases of the nervous system, neural signaling, neurophysiology, neurotoxicology, neuroendocrinology, and neuroimmunology. The successful candidate will have 1) a PhD in Biological Sciences or related field, 2) a proven record or demonstrated potential to obtain external funding to support an active research program, 3) a growing record of scholarship and publication in higher-tier journals appropriate to the applicant’s field of study, and 4) an academic record demonstrating the potential for excellence in undergraduate and graduate teaching.

Start Date: August 2022

Deadline: The review of applications will begin on January 15, 2022, and will continue until the position is closed.

Application Procedures: Apply at https://jobs.untsystem.edu/postings/53887 and include the following items: 1) curriculum vitae, 2) cover letter, 3) 3 sample publications, 4) contact information for three referees, 5) statement of research Interests (≤ 2 pages, single-spaced) and 6) statement of teaching philosophy (≤ 1 page), including experience/interests in including underrepresented groups.

The University of North Texas System and its component institutions are committed to equal opportunity and comply with all applicable Federal and state laws regarding nondiscrimination and affirmative action. The University of North Texas System and its component institutions do not discriminate on the basis of race, color, sex, sexual orientation, gender identity, gender expression, religion, national origin, age, disability, genetic information, or veteran status in its application and admission processes, educational programs and activities, and employment practices. UNT has a highly diverse campus with a wide range of languages spoken in addition to English. We welcome candidates who have experience with HSI/MSIs and/or who speak Spanish, Vietnamese, American Sign Language, Chinese (Cantonese, Mandarin and other variations), Arabic, Tagalog, Farsi, French, or/and Yoruba.

Questions concerning the position should be directed to Dr. Pudur Jagadeeswaran, Search Committee Chair (jag@unt.edu).

The Sokol laboratory at the Icahn School of Medicine at Mount Sinai, New York,is looking for a motivated postdoctoral scientist to join our group in the winter/spring of 2022. Our group studies how embryonic Wnt and planar cell polarity (PCP) signaling pathways regulate cell movements during gastrulation and neural tissue development. A successful candidate will use live cell imaging and genomic/proteomic approaches to study how signaling molecules and mechanical forces regulate cell shape changes and cell movements in Xenopus and zebrafish embryos. Read more at in our recent papers and at http://labs.icahn.mssm.edu/sokollab/ . Our laboratory is in the Department of Cell, Developmental and Regenerative Biology, with a number of groups with highly collaborative, developmental and stem cell biology program. Besides high-quality research core facilities, career guidance and professional development training are provided for postdoctoral fellows.

Preference will be given to recent graduates with strong background in cell biology, biochemistry, genomics or bioinformatics. Salary will be commensurate with experience. Potential candidates may send their CV, a short description of relevant expertise and research interests, list of publications and the names of three references to Dr. Sergei Sokol (sergei.sokol@mssm.edu).

Job Summary:

The Research Assistant will be responsible for fish care and maintenance in the Institution’s zebrafish ( Danio rerio) research facility. Also provides assistance with experimental work and sample analysis involving zebrafish and killifish. Excellent communication and organizational skills, attention to detail, and ability to work independently, effectively, and productively are required. The successful candidate needs to work as part of a team and be able to coordinate effectively with the zebrafish facility users (3 PIs). This is a Woods Hole, land-based position.

Major Duties:

  • Perform all necessary tasks to keep the fish in good health. Including, but not limited to:

  • General zebrafish husbandry and maintenance.

  • Maintenance and breeding of various mutant and transgenic fish lines.

  • Genotyping of mutant lines

  • Overseeing the operation and upkeep of the facility

  • Raising live feed ( Artemia)

  • Maintaining water quality

  • Detailed record-keeping

  • Must be willing to work flexible hours to accommodate facility needs.

  • Provides assistance with laboratory safety programs.

  • Opportunities for involvement in related research involving cell culture, molecular biology assays.

Education Desired:

Bachelor’s Degree or Associate’s Degree in related field plus one year related experience. Experience in fish culture and/or molecular assays (DNA isolation; polymerase chain reaction (PCR)) a plus.

To apply:

https://careers-whoi.icims.com/jobs/1597/research-assistant---zebrafish/job (Job 2021-1597)

Questions: mhahn@whoi.edu

Postdoctoral Research Fellow, Goldman Lab, Michigan Neuroscience Institute, University of Michigan

Job Summary

Our research aims to restore sight to the blind using regenerative approaches. We seek a recent PhD that is highly motivated, bright and creative to join our group and to help further characterize mechanisms underlying retina regeneration in zebrafish and mice. We are using RNAseq, CRISPR/Cas9, transgenic and other molecular and cellular approaches to identify the mechanisms by which zebrafish regenerate a damaged retina. Signal transduction pathways and gene expression programs that drive retina regeneration in fish will be discovered and characterized. Factors stimulating retina regeneration in fish will be applied to mice to determine if retina regeneration can be stimulated in a mammalian model. Research Fellows are expected to work independently and in teams; design and implement new research strategies; collect and analyze data; write research manuscripts for publication; and apply for funding. For more information please visit: https://medicine.umich.edu/dept/mni/daniel-j-goldman-ph-d and https://medicine.umich.edu/dept/mni/research-highlight-retina-regeneration

Required Qualifications

Recent Ph.D. in neuroscience or related biological discipline. Previous research experience using zebrafish as a model systems. Multiple publications in high quality journals demonstrating research experience and productivity. Proficient in the techniques of molecular and cellular biology.

Desired Qualifications:

Strong communication and writing skills. Can-do attitude. Previous research studying retina regeneration and/or stem cells. Experience using advance microscopy techniques and high throughput approaches to studying gene expression like scRNAseq and ATACseq.

Applicant Instructions

Interested applicants should email their CV, a cover letter describing their research experience, interests and goals, and names/contact information for three academic references to the attention of Dan Goldman at neuroman@umich.edu

Senior Laboratory Research Scientist – Developmental Signalling Lab, The Francis Crick Institute, London

Closing Date:

07/Jan/2022 23.59 GMT

Job Description:

The Francis Crick Institute Developmental Signalling Laboratory, led by Caroline Hill, is seeking a highly motivated Senior Laboratory Research Scientist (SLRS) with expertise in zebrafish development to support ongoing projects in the lab as well as to lead their own independent research project. The successful candidate will manage day-to-day lab operations and the lab budget, train PhD students and postdocs, and will drive their own independent project focused on predominantly on using zebrafish as a disease model. They will also support other research in the lab where appropriate and help generate and maintain zebrafish lines. The successful candidate should be strongly motivated to do research as well as having good organisational skills to be able to successfully manage the lab operationally.

Project summary

The Hill lab is focused on understanding how TGF-β family signalling pathways function normally during early vertebrate development and in adult untransformed tissue culture cells, and how deregulated TGF-β family signalling causes diseases like cancer and the Marfan syndromes. To do this they exploit the very powerful combination of early vertebrate developmental systems (zebrafish embryos), together with a variety of model tissue culture systems, and mouse models. Methodologies used range from developmental and cell biology and next generation sequencing to computational modelling. Excluding the current vacancy for the SLRS, the group comprises around ten people - a mixture of postdocs, PhD students and masters students. Four of the lab members focus primarily on working on these signalling pathways in the context of zebrafish development, whilst the others focus on the more mechanistic and disease aspects of signalling, using in vitro models and mouse models.

For more information about the lab and current research see https://www.crick.ac.uk/research/labs/caroline-hill

For some recent publications see:

https://pubmed.ncbi.nlm.nih.gov/34737283/

https://pubmed.ncbi.nlm.nih.gov/34003511/

https://pubmed.ncbi.nlm.nih.gov/33416497/

https://pubmed.ncbi.nlm.nih.gov/29275993/

The main project that the SLRS will focus on concerns determining how deregulated TGF-β family signalling leads to diseases such as the Marfan syndromes. The SLRS will use CRISPR/Cas9 editing in zebrafish embryos to generate zebrafish models of these diseases to unravel the underlying molecular mechanisms. Candidates with a strong proven expertise in zebrafish embryology and genetics and in molecular biology are encouraged to apply.

Key responsibilities

These include but are not limited to:

Carrying out research projects independently and in collaboration with other members of the lab.

Generating and maintaining zebrafish lines

Lab management – day-to-day operation of the lab, e.g. ordering reagents, equipment care, managing the lab budget, database management etc

Representing the lab when necessary in the Institute

Training new lab members

Support lab members, including PhD Students, providing advice and guidance as required

Key experience and competencies

The post holder should embody and demonstrate our core Crick values: bold, imaginative, open, dynamic and collegial, in addition to the following :

Essential

Qualifications, experience and competencies:

PhD in developmental biology

Good knowledge and experience of working with zebrafish as a developmental system and technical expertise in zebrafish embryology and imaging

Good knowledge and experience of molecular biology

Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals

Ability to work independently and also in a team

Strong organisational skills and thorough record-keeping

Excellent oral and written communication skills and the ability to provide feedback and guidance to other lab members and teams where needed

Good interpersonal skills enabling the postholder to influence and build effective relationship both within the lab and in collaboration with colleagues

Strong interest in pursuing independent research

Desirable

Qualifications, experience and competencies:

Experience in signal transduction research

Experience with mouse models

To apply follow this link: https://crick.wd3.myworkdayjobs.com/External/job/London/Senior-Laboratory-Research-Scientist---Developmental-Signalling-Lab_R543-2

For more information, please contact Caroline Hill (caroline.hill@crick.ac.uk)

Postdoctoral Research Associate-Washington University School of Medicine, Department of Developmental Biology

The Solnica-Krezel and McNeill labs are looking for a joint postdoctoral fellow for a collaborative project on the mechanisms of vertebrate planar cell polarity and morphogenesis. The project will explore the relation of Ds/Fat cadherins and core planar polarity genes in sculpting the vertebrate body plan. High resolution imaging, genome editing and in vivo proteomics approaches in mouse and zebrafish will investigate the cell polarity and migration in neural and mesenchymal tissues during embryogenesis.

For more information on the McNeill and Solnica-Krezel labs, please visit our websites at McNeill Lab and Solnica-Krezel Lab.

Required Qualifications

Ph.D. degree in molecular biology, genetics, developmental biology, cell biology, biochemistry or similar fields.

Published in high-quality peer-reviewed journals.

Ability to guide research projects and maintain detailed records of experimental work.

Background in or strong desire to learn cell and developmental biology.

Good interpersonal skills and willingness to mentor trainees and technicians.

Excellent speaking, reading and writing skills.

Applicant Special Instructions

Interested candidates should apply by visiting jobs.wustl.eduand search for JR63612 or send a cover letter, CV, contact information for three references and one key first author publication directly to tonihill@wustl.edu.

North lab: Postdoctoral Research Fellow

North Laboratory

Stem Cell Program

Division of Hematology/Oncology

Boston Children’s Hospital

Harvard Medical School

Job description

Full-time funded postdoctoral research positions in the field of hematopoietic (blood) stem cell (HSC) biology are available in the North laboratory in the Stem Cell Program, Division of Hematology/ Oncology at Boston Children’s Hospital (BCH) and Harvard Medical School. The North lab aims to understand the regulatory networks controlling the specification, expansion and function of HSCs to aid development of translational strategies to direct their de novo production for therapeutic use. Our ongoing investigations utilize molecular genetics, chemical biology, transcriptomics, and multiphoton imaging techniques in zebrafish, mouse and human iPSC models to identify and characterize pathways regulating HSC development in vivo and in vitro.

The position offers an exciting opportunity to engage in cutting-edge work at the interface of basic and translational research in a highly collaborative and stimulating training environment in the vibrant Harvard Medical School Community. For more information on research in the North lab, please visit: https://www.childrenshospital.org/research/researchers/n/trista-north

Job Requirements

Candidates should have (or be on track to complete) a Ph.D. or an M.D./Ph.D or equivalent training. A strong background in one of more of the following areas is preferred, but not required: hematology, developmental or stem cell biology, genetics, molecular biology, bioinformatics.

Apply

Interested applicants should email their CV, a cover letter describing their research experience, interests and goals, and names / contact information for three academic references to the attention of Dr. Trista E. North (Trista.north@childrens.harvard.edu).

Employing Department and Institution:

Stem Cell Program, Division of Hematology/Oncology, Boston Children’s Hospital

Research Technician

Aquatics

Job ID:

REQID0001832

The Stowers Institute for Medical Research has an opening for a full-time Research Technician in the Aquatics Zebrafish Facility.

Responsibilities Include:

  • Providing routine care and husbandry of fish including feeding, water exchanges, tank cleaning, and health monitoring.

  • Developing and modifying animal care policies, standard operating procedures, and practices which promote high-quality, cost-effective operation of the facility.

  • Interacting with faculty, staff, and other teams to provide high quality, responsive animal care services.

  • Monitoring supply and equipment inventory to sustain day-to-day operations.

  • Maintaining accurate records including room logs, health reports, animal census, and other records as required.

  • Preparing for all regulatory inspections.

Prior experience with aquatic animals and a basic understanding of system maintenance relating to recirculating aquaculture systems is preferred. The candidate will be required to gain ALAT certification through AALAS. Weekend and Holiday work will be required.

Minimum Requirements:

  • Bachelor’s degree in any of the life sciences (e.g., animal science, biology, microbiology, aquaculture).

  • Basic computer skills and a working knowledge of computer programs including Microsoft Outlook, Excel, and Word.

  • Self-motivation, excellent communication and organizational skills, and the ability to work closely with other team members.

To Apply

Submit the requested documents to careers@stowers.orgor to Administration Department, Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110.

Requested Documents

  • Current Resume

  • Cover Letter

https://www.stowers.org/careers/explore/research-technician-aquatics-reqid0001832

A post-doctoral fellow position is available in the laboratory of Dr. Xiaolei Xu, Professor of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine. The successful applicant will join a team that is leveraging powerful zebrafish genetics to model human cardiovascular diseases, to decipher underlying mechanisms, and to develop new therapies. Applications are invited from candidates who have a strong background in molecular biology, genetics and/or cardiovascular diseases. Previous experience in animal models of human diseases and/or bioinformatics are favored, but not required. Qualified candidates must be self-motivated and have a strong commitment to basic research. Further enquires (enclosing a CV) regarding the scope and detail of the project should be addressed to: xu.xiaolei@mayo.edu or visit +https://www.mayo.edu/research/labs/zebrafish-genetics +

Mayo Clinic College of Medicine is a not-for-profit organization that integrates research with clinical practices and education in multi-campus environment. Mayo offers an attractive benefit package. Salary will be determined by the successful candidate's experience.

Applications, including curriculum vitae and bibliography, summary of past accomplishments, and the names of three references, should be sent to:

Xiaolei Xu, PhD.

Mayo Clinic

Stabile 4-10

200 First Street SW

Rochester, MN USA 55905

Email: xu.xiaolei@mayo.edu

Phone number: 507-284-0685