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  • Work with research animals including mouse or zebrafish manipulation, and analyze data generated with such models

  • Carry out phenotypic and genotypic screening of mutant and transgenic lines.

  • Perform basic molecular biology manipulations such as DNA/RNA/protein purification and quantification, expression vector construction, morpholino injection and CRISPR/Cas9 gene editing.

  • Express mutant proteins in vitro to examine effects such as protein stability, cell/nuclear morphology and the cell cycle.

  • Perform embryo/cell imaging experiments including fixed and live-cell confocal microscopy.

  • Analyze human genetic variants for their effects on specific protein domains and cellular functions.

  • Interact with a team of trainees, technical staff, and faculty to optimize laboratory techniques and oversee the day-to-day management of multiple projects, performing advanced experimental design, optimization and interpretation.

  • Perform other duties as assigned, including assistance with posters, manuscripts and grant proposals.

Required Knowledge/Skills/Abilities: