A postdoctoral researcher position is available in the laboratory of Dr. Jingli Cao at Weill Cornell Medical College, Cornell University in New York City. The Cao lab is located in the Cardiovascular Research Institute (CVRI) and the Department of Cell & Developmental Biology. We aim to understand the basic mechanism of innate tissue regeneration by focusing on heart regeneration. The lab uses a combination of zebrafish model, explant tissue culture, human stem cells, high-throughput sequencing, chemical screening, live imaging, and genome editing approaches (such as CRISPR/Cas9). Please refer to our website (www.caolab.net ) and recent publications for further information (Dev. Cell, 2017. 42: 600; Nat. Protoc., 2016. 11(5):872;Development, 2016. 143(2):232; Nature, 2015. 522(7555): 226).
Highly motivated individuals with interests in the field of tissue regeneration, heart disease and repair, and zebrafish model are encouraged to apply. The candidates with research experience in cell biology, developmental biology, and animal models are preferred, but not required. Candidates must hold a Ph.D. degree or equivalent. The successful applicants will join a dynamic team of scientists at CVRI and benefit from the unique, collaborative Tri-Institutional research environment (Weill Cornell Medical College, The Rockefeller University, and the Memorial Sloan Kettering Cancer Center). Weill Cornell Medical College offers subsidized housing and excellent benefits.
The positions will remain open until filled. Please send a cover letter describing their research background, interests, career goals, alongside a CV and names and contact information of three references in a single PDF file to Dr. Jingli Cao at jic4001@med.cornell.edu.
A phylogenetically anchored multi-OMICS approach to chemical hazard prediction
A postdoctoral position is available as part of the EU H2020 project “PrecisionTox: Toward Precision Toxicology: New Approach Methodologies for Chemical Safety” at the IBCS-BIP/Karlsruhe Institute of Technology.
The project aims to use OMICS data from a range of divergent model organisms to derive phylogenetically conserved predictors of adverse compound effects. Organisms will be exposed to a set of 250 model compounds and data on transcriptomic and metabolomic effects of the exposure will be acquired. Selected compounds will be chosen for fine-grained mechanistic studies, involving e.g. single cell RNAseq or automated behavioral assays, thereby linking altered patterns of gene expression and metabolism to physiological effects. These data will reveal which specific changes in genetic and metabolic markers predict compound-induced hazardous alterations of specific organismal functions.
In your project, you will be responsible for the zebrafish part of the project. You will conduct the initial exposure and sampling experiments and contribute to data analysis within the consortium. You will flag compounds for detailed analysis employing the wealth of resources for OMICS, genetics and imaging studies available in the zebrafish model system. From these studies, you will derive new insights on how compound induced (de-)regulation of gene expression and metabolism impacts on embryonic development, physiology and/or behavior.
The IBCS-BIP at the Karlsruhe Institute of technology (KIT) offers excellent laboratory space and equipment, state of the art fish facilities, a zebrafish screening center and a stimulating scientific environment. The KIT also hosts the European Zebrafish Resource Center (EZRC), which allows for easy access to a wealth of transgenic lines and mutants. Outside KIT, project partners include groups at universities, research institutes and companies, for example in Birmingham, Leipzig and Paris.
The position is available immediately. Funding is initially provided for a period of 1 year (full-time), with the possibility of extension for up to 3 years. Part-time employment is also possible.
Eligible candidates should hold a doctoral degree in life sciences and should have a strong background in OMICS technologies. Previous experience with zebrafish and/or with chemical screening technologies are additional assets.
KIT aims to balance the number of female and male employees. We therefore kindly ask female researchers to apply. If qualified, applicants with disabilities will be preferred.
Applications must include a letter of motivation, an informative CV, a list of publications, and the names and contact details of at least two potential referees.Application deadline is April 7th, 2021. All documents should be merged into a single pdf file, labelled with the applicant´s surname, and be sent by email to:
Dr. Thomas Dickmeis
Karlsruhe Institute of Technology (KIT)
Institute of Biological and Chemical Systems – Biological Information Processing (IBCS-BIP)
Karlsruhe, Germany
Email: thomas.dickmeis@kit.edu
Web: https://bip.ibcs.kit.edu/index.php
Description
The Chan Zuckerberg Biohub ("CZ Biohub”) is an independent nonprofit medical research organization based in the San Francisco Bay Area. The Chan Zuckerberg Biohub supports scientific research to cure, prevent or manage disease in our children’s lifetime. Our mission is to understand the fundamental mechanisms underlying disease and to develop new technologies that will lead to actionable diagnostics and effective therapies. We harness the power and possibility of collaboration to drive discovery and set the standard for open, impactful science. For more information, please visit czbiohub.org.
As part of our Cell Atlas Initiative, the CZ Biohub has started a collaborative effort towards building a multimodal Cellular Atlas of the Vertebrate Development using zebrafish as model organism.
Opportunity
We are currently seeking an outstanding Research Scientist to join our collaborative and interdisciplinary project at the interface between imaging and sequencing. The individual will be embedded in the team led by Loic A Royer, and will be in charge of developing innovative sequencing pipeline and genetic tools for the project. The candidate will work on cutting edge technology development combining genetic engineering, single-cell sequencing, CRISPR-Cas9, zebrafish transgenesis, and state-of-the-art imaging using a wide array of modern technologies. This an exciting chance to be embedded in a highly collaborative and well-funded project, with great opportunities for learning and skill development. We are looking for a team player with strong technical skills in addition to excellent communication skills. The ideal candidate will be capable of experimental design, execution, troubleshooting and data analysis.
Responsibilities
- Single cell dissociation and sorting from fresh fish embryos
- NGS library preparation, sequencing, and sequence analysis
- Development of genetic construct for imaging and sequencing
- Transgenesis using CRISPR in zebrafish
Requirements
- PhD in Molecular and Cell Biology or a related discipline, or Bachelor’s/Master’s degree for exceptional candidates with proven relevant experience and strong publication track record
- Molecular biology (cloning, RNA extraction, PCR techniques, among others)
- Experience with cell sorting
- NGS library prep, sequencing, analysis
- Must be highly collaborative, team-oriented and have excellent written and oral communication skills.
Desired Experience
- CRISPR-based genome editing, preferably in Zebrafish.
- Programming experience in Python (preferably) or R
- Experience with fluorescence imaging
IMPORTANT NOTE: Applications without a cover letter have a low chance of success.
A postdoctoral fellowship/senior research associate position is currently available in the Mchaourab lab at Vanderbilt University in Nashville, TN. The project entails the use of zebrafish as an experimental model to understand the proteostasis network in the lens and heart. We apply advanced genetic approaches, including transgenesis and genome editing (such as CRISPR/Cas9), and microscopic imaging techniques to decipher the functional roles of small heat shock proteins for the maintenance of transparency during lens aging as well as stress resistance of the heart. Our recent discovery revealed a direct coupling between proteostasis and cortisol stress signaling and future directions will seek to investigate the mechanistic bases of this coupling.
We are a highly interdisciplinary group with interest ranging from chaperones to multidrug transporters. The laboratory is located in the department of Molecular Physiology and Biophysics with access to state of the art cores in fluorescence microscopy, mass spectrometry and various biophysical instrumentation. The position will provide opportunities for applying mechanistic biochemistry in vitro to complement the in vivo genetic analysis as well as learning advanced biophysical techniques.
Candidates should have a Ph.D. in biochemistry, cell biology, genetics, or related fields. The ideal candidate will have expertise in microscopy, image analysis, and modern molecular biology techniques and with previous experience in zebrafish rearing and husbandry.
If you are interested, send CV to hassane.mchaourab@vanderbilt.edu
Assistant Professor (Tenure-track) position in Integrative Animal Biology at Syracuse University
The Department of Biology at Syracuse University (biology.syr.edu) is seeking applications for a tenure-track Assistant Professor position in the field of Integrative Animal Biology. This position is part of an ambitious Invest Syracuse Cluster Hire Initiative in the broad area of bioinspired science and technology. As an integral part of this investment, Syracuse University is actively recruiting multiple candidates for tenured/tenure-track faculty positions for a cohesive research cluster in the focus area of form and function which seeks to understand and optimize movement in organisms, robots, and human-machine interfaces. Faculty hired into this position will build on existing strengths in the focus area and establish their lab in the Biology department with access to the world-class facilities of the multidisciplinary BioInspired Institute that spans multiple departments in the College of Arts and Sciences and the College of Engineering and Computer Science. Further information on the BioInspired Institute and the campus-wide hiring initiative can be found at bioinspired.syr.edu.
Candidates should have a Ph.D. in a relevant area of biology or a closely related field and research experience employing an integrative approach to answer fundamental questions in biology. Preference will be given to candidates with expertise in the areas of evolutionary biomechanics and functional morphology with a research focus on the diversity and evolution of animal function. Syracuse University is particularly interested in candidates who demonstrate past accomplishment toward fostering diversity and building an inclusive climate in research and/or teaching to maximize their effectiveness interacting with diverse groups of colleagues, students and community members. The candidate is expected to develop an internationally recognized, externally-funded research program and participate in graduate and undergraduate teaching and mentoring in the areas of their expertise.
A strong commitment to collaborative, cross-disciplinary research is especially desirable. The selected candidate will complement existing strengths in the Biology Department at Syracuse University including Evolution and Animal Behavior; Genetics, Genomics and Epigenetics; Neuroscience; Ecology and Plant Biology; and Cell, Molecular and Developmental Biology. The Department of Biology also has strong research and educational ties to the adjacent Upstate Medical University and the State University of New York College of Environmental Science and Forestry.
For full consideration, candidates must complete an online application and electronically submit a cover letter, curriculum vitae, concise statements of research plans and teaching interests, a diversity statement describing interest or efforts in furthering diversity and inclusion, .pdfs of two representative articles demonstrating fit with the position, and contact information of three professional references through www.sujobopps.com (job 075581, https://www.sujobopps.com/postings/85906). Review of applications will start on March 15, 2021 and continue until the position is filled.
Competitive salary, start-up funds, and laboratory space will be provided. Located between the Adirondack Mountains, Finger Lakes, and Lake Ontario regions of upstate New York, the metropolitan area of Syracuse boasts myriad cultural and recreational opportunities and offers a wide array of urban, small town, and rural living. For additional information, please contact the chair of the search committee, Susan Parks at sparks@syr.edu.
Syracuse University is an equal opportunity/affirmative action employer with a strong commitment to equality of opportunity and a diverse work force. Members of groups traditionally underrepresented in higher education are strongly encouraged to apply.
Assistant Professor – Bioinformatics
The Department of Biology at Syracuse University seeks applicants for a tenure-track position in Bioinformatics at the Assistant Professor level. Candidates should have demonstrated bioinformatics and computational biology research experience that complements existing departmental strengths in Genetics, Genomics and Epigenetics; Cell, Molecular and Developmental Biology; Evolution and Animal Behavior; Neuroscience and Ecology and Plant Biology. Candidates must have expertise in the application of bioinformatics techniques and should be interested in the development of novel statistical and algorithmic approaches, potentially including Machine Learning, Artificial Intelligence, Data Analytics and Optimization Algorithms. The candidate is expected to develop a vigorous externally funded research program and participate in graduate and undergraduate teaching and mentoring in the areas of his or her expertise. Candidates must have a PhD in a relevant area of biology and an outstanding record of research experience at the postdoctoral level.
This recruitment is part of the ambitious Invest Syracuse Big Data Initiative in the broad area of Genomics, Bioinformatics, Data Sciences and Analytics. Faculty hired into these positions will join a highly collaborative group of biologists and will contribute to a multidisciplinary research cluster that spans multiple departments in the College of Arts and Sciences, the College of Engineering and Computer Science, Falk College and Whitman School of Management. The Department of Biology also has strong research and educational ties to the adjacent Upstate Medical University and the State University of New York College of Environmental Science and Forestry.
Applicants should submit a cover letter, curriculum vitae, statements of research and teaching interests, a diversity statement describing interest or efforts in furthering diversity and inclusion, and arrange for three reviewers to submit recommendation letters to https://www.sujobopps.com/postings/85905, by March 15th, 2021. The search will remain open until the position is filled. Syracuse University is interested in candidates who have the communication skills and cross-cultural abilities to maximize their effectiveness with diverse groups of colleagues, students and community members. Women, military veterans, individuals with disabilities, and members of other traditionally underrepresented groups are encouraged to apply.
Syracuse University is an equal opportunity employer, as well as a federal contractor required to take affirmative action on behalf of protected veterans.
Competitive salary, start-up funds, and laboratory space will be provided. Located between the Adirondack Mountain, Finger Lakes, and Lake Ontario regions of upstate New York, the metropolitan area of Syracuse boasts myriad cultural and recreational opportunities and offers a wide array of urban, small town, and rural living. Questions can be addressed to search chair Steve Dorus at sdorus@syr.edu.
The Max Planck Institute for Brain Research (MPI for Brain Research) in Frankfurt/Main is a vibrant research institution in the field of basic research in Neuroscience with a focus on understanding the functions of the brain’s circuits. The institute is located in a state-of-the-art research building on Campus Riedberg (housing approx. 300 employees) with modern labs, animal husbandry and support facilities (www.brain.mpg.de).
Our researchers from many different backgrounds (e.g., molecular biology, genetics, electrophysiology, imaging, behavior, physics, computer science and mathematics) collaborate in an interactive and integrative environment to investigate the structure and function of neuronal networks.
The Schuman Lab (Department of Synaptic Plasticity) is looking for (a)
Postdoctoral Fellow(s) (m/f/div)
to examine the neural substrates of learning, memory and social behavior at the synaptic and network level using zebrafish (e.g. Anneser et al., Nature, 2020; https://doi.org/10.1038/s41586- 020-2988-z).
The ideal candidate has a Ph.D. and is an independent and creative thinker with a strong work ethic and significant experience using zebrafish and molecular biology, imaging and/or behavioral testing. This position is a unique opportunity to work in a highly interdisciplinary environment that is equipped with a new, state-of-the-art fish facility, as well as ample imaging and electrophysiology resources.
The Max Planck Society is an equal opportunity employer and is striving to increase the proportion of women in areas where they are under-represented. It therefore expressly encourages female applicants. The Max Planck Society is striving to employ more individuals with disabilities. It therefore expressly encourages applicants with disabilities.
Please send your application electronically as a single pdf document including a concise statement of research interest, CV, and contact information for three letters of reference to anita.kulak@brain.mpg.de
Erin M. Schuman, Ph.D.
Technologist II - RI
Position Description
Under the supervision of the Investigator, the technologist will assist with neurobehavioural research. Specifically, our lab focuses on understanding the molecular and synaptic mechanisms underlying social memory using mouse and zebrafish models.
Here's What You'll Get To Do:
- Performing electrophysiology, molecular biology, imaging and behavioural experiments
- Maintaining animal colonies
- Collecting experimental data, verifying results, performing analysis and passing on findings
- Working in collaboration with team of researchers and trainees
Here's What You'll Need:
- Recent Masters or Bachelor's Degree in Physiology, Neuroscience, Molecular Genetics, Cell Biology or equivalent degree
- Minimum 2 years relevant experience preferably in a basic neuroscience research laboratory setting
- Experience working with mice and/or zebrafish is preferred
- Electrophysiology experience is considered an asset
- Minimum one (1) year of experience with molecular biology techniques (e.g. cloning, PCR, western blotting, preparation of buffers and standard solutions), genetic methods (e.g. the design and execution of genetic crosses), and microscopy techniques, including preparation of specimens for immunofluorescence microscopy
- Demonstrated experience interpreting experimental results, troubleshooting experiments, and managing priorities and deadlines
- Experience with computer software tools (e.g. Microsoft Office, R/SPSS, and Adobe Photoshop/Illustrator)
- Coding experience preferably Python is an asset
- Experience with online molecular biology analysis tools (e.g. BLAST and primer design tools)
- Strong oral and written communication skills, ability to exercise initiative and deal effectively with other lab members
Employment Type: Full-time 15 Month Contract with a possibility of extension, 1.0 FTE
A complete application should include a statement of interest, a CV, and the names of 2 references. Once the suitable candidate is identified, the position will commence immediately upon completion of the necessary paperwork. The position will remain open until filled.
Our Commitment to Diversity
The children and families we care for are diverse, and so are our employees. All are welcome to join our unique organizational culture and be part of our inclusive team.
If requested, SickKids is proud to make available accommodations to support applicants with disabilities during the interview and assessment process. Information received relating to accommodation will be addressed confidentially. SickKids is also committed to providing services in both official languages and our preference is to hire employees who are fluent in both English and French whenever possible.
Thank you for your interest in joining SickKids. Only those applicants selected for an interview will be contacted. In accordance with our Hospital policy, employment at SickKids is conditional upon the Hospital’s receipt of all necessary documentation.
How to Apply
Please use the following link to view the complete posting and to apply.
Tip: Combine your cover letter and resume into ONE document of 20 pages or less as you cannot upload multiple documents as part of your application.We are hiring a Research Technologist to start in February or March. They will assist with neurobehavioural research. Specifically, our lab focuses on understanding the molecular and synaptic mechanisms underlying social memory using mouse and zebrafish models.