Blog from September, 2022

Job Title: NIH Postdoctoral Fellow or Research Fellow – Westlake Lab

National Cancer Institute,  Laboratory of Cell and Developmental Signaling
Section: Membrane Trafficking and Signaling Section
PI: Chris Westlake, Ph.D.

Website: https://ccr.cancer.gov/staff-directory/christopher-j-westlake

Job Description:

  • Employ the zebrafish model to investigate protein function associated with cilia and ciliopathy by designing research protocols and collecting and managing data

  • Micro-injection of mRNA, morpholinos, and Crispants (CRISPR-Cas9) into embryos

  • Embryo/cell imaging experiments (fixed and live cell confocal and super resolution microscopy and electron microscopy)

  • Molecular biology (morpholino and CRISPR guide RNA design, cloning, DNA and RNA prep)

  • Biochemical analysis (immunoblotting, immunoprecipitation etc)

  • Screening (genotyping) of transgenic fish lines

  • Documents research results, statistic analysis and interpretation of data, presentation of results in group meeting and participates in publication preparation of results

Requirements:

  • Have previous experience in animal models of human diseases, preferably zebrafish or other aquatic animals

  • Must have a PhD or MD

  • Research Fellow position will be considered for candidates with previous postdoc experience

 

Please email chris.westlake@nih.gov a CV, statement of research interests, and names of three references with email addresses and phone numbers. Please write “Zebrafish Fellow application” in the subject heading.

The Kucenas Lab in the Department of Biology and Program in Fundamental Neuroscience at the University of Virginia has an open position for a post-doctoral scholar to investigate the cellular and molecular mediators that govern glial tiling in developing and diseased nervous systems.

This position, fully supported by the Owens Family Foundation and the NIH, involves basic and translational research using zebrafish and we are seeking an enthusiastic, focused and creative candidate to join our team. You will be able to make a significant contribution to the ongoing research of the Kucenas Lab through the design and execution of experiments along with appropriate data analysis approaches. An essential part of the role is to disseminate findings by writing papers and presenting ongoing work at conferences and seminars. By working alongside PhD students, technical staff, and undergraduate students, you will also have opportunities to develop your mentoring and teaching skills. You will work within the Biology Department and Program in Fundamental Neuroscience, a supportive and collaborative collective of researchers using model organisms to address a broad range of neuroscience research questions.

We have strong links with colleagues across the university and have developed additional collaborative links for this project with labs within the School, as well as elsewhere in the US. Numerous opportunities for further training and career development are offered by the University of Virginia, all within one of the most beautiful cities on the east coast. In the Kucenas Lab, we build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching, and student experience and we do not tolerate discrimination of any kind. Our lab is located in Gilmer Hall at UVA in Charlottesville, Virginia and is within a 10-minute walk of the Medical Center, which provides exceptional opportunities for collaboration among basic and clinical scientists. Our scientific community is heavily invested in training, and we work hard to help trainees develop the skills necessary for successful independent careers.

REQUIRED QUALIFICATIONS:

Candidates must have a Ph.D. in Neuroscience or a related discipline (i.e. Biology, Cell and Developmental Biology, etc.) by the start date of this position. Candidates must have a strong motivation for and commitment to research in cellular, molecular, and developmental neuroscience. Prior experience working with zebrafish embryos, with strong experimental skills including zebrafish transgenesis, live imaging and quantitative image analysis approaches, are desirable. The ability to work independently is essential, while maintaining a strong team ethic with excellent communication skills. The post demands a flexible attitude and an ability to respond positively to the challenges faced in the research environment.

APPLICATION PROCEDURE:Apply online at https://uva.wd1.myworkdayjobs.com/en-US/UVAJobs/details/Research-Associate-in-Biology_R0040806 and attach the following;

  • cover letter. In the cover letter, please address your experience relevant to the research project.

  • curriculum vitae.

  • contact information for three individuals who can provide professional reference letters.

Please note that multiple documents can be uploaded in the box.

PPLICATION DEADLINE:Review of applications will begin on October 10, 2022. The University will perform background checks on all new hires prior to employment.

This is a one-year appointment; however, the appointment may be renewed for an additional two, one-year increments, contingent upon available funding and satisfactory performance.

For any questions about the position, please contact Sarah Kucenas, Professor, at sk4ub@virginia.edu.

For questions about the application process, please contact Richard Haverstrom, Faculty Search Advisor, at rkh6j@virginia.edu.

Applications by members of underrepresented groups are strongly encouraged.

For information on the benefits available to postdoctoral associates at UVA, visit http://postdoc.virginia.edu and http://hr.virginia.edu/benefits .

COVID Vaccination Requirement and Guidelines

Please visit the UVA COVID-19 Job Requirements and Guidelineswebpage prior to applying for current information regarding vaccination requirements and guidelines for employment at UVA.

The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.

Engineer position in the IMAGINE Institute, Paris, France: zebrafish genome editing

Advances in sequencing technologies and generalization of their use in genetic diagnosis has dramatically increased the rate of identification of new candidate variants for rare genetic diseases. Validating the implication of these variants in disease, and understanding the pathological mechanisms involved, represent the next challenges in the field. In particular, the impact of missense variants is hard to predict, and requires the generation of specific models for investigation. In recent years, zebrafish have emerged as a powerful model to investigate human genetic diseases. The development of directed mutagenesis using CRISPR/Cas9 technologies has increased further the value of the zebrafish model. Within the Imagine Institute, we are initiating a collaborative project between five teams, working in synergy to test and optimize different techniques for precise genome editing in zebrafish. Within the frame of this project, we are recruiting an engineer to participate in the implementation of these approaches (2 years-contract).

Description of duties

  • Design strategies for genome editing, together with consortium researchers

  • Perform regular surveys of the literature in the field of genome editing

  • Test and optimize the efficiency of editing with different approaches in zebrafish

  • Establish new edited zebrafish lines (injections, screening, genotyping)

  • Maintain and manage generated lines in the animal facility

  • Write and share validated protocols

  • Present results during internal meetings and in external meetings/workshops

  • Ordering and managing the stocks of consumables for the project

Education/Experience

  • The candidate should have a Master degree in molecular biology, genetics or any related field

  • Excellent technical skills in molecular biology (PCR, cloning, sequence analysis)

  • Prior experience with the zebrafish model is highly preferred

  • Good knowledge of the English language

Skills

  • Dynamism and enthusiasm for developing, optimizing and troubleshooting new techniques

  • Excellent organization and time-management skills

  • Scientific rigor

  • Team worker with good communication skills.

Work environment:

The Imagine Institute, located in the heart of Paris, is the leading European center for research, care and education on genetic diseases (https://www.institutimagine.org/en ). The Institute brings together 1000 of the best doctors, researchers and healthcare personnel in a creative architecture of synergies, to accelerate research and develop innovative care.

Start date: the position is available from now

Term of employment: 2 years contract (short-term, CDD Imagine), salary depending on experience

To apply: Please send a CV, a motivation letter and 2 references to marion.coolen@inserm.fr and emilie.dambroise@institutimagine.org

Villanova University’s Department of Biology invites applications for a Tenure-Track ASSISTANT PROFESSOR position, beginning August 2023. Research in the Department ranges from molecules to ecosystems, and we embrace diverse approaches. We encourage applications from geneticists who work in any one of a variety of disciplines. Our new colleague will establish a productive research program, integrate undergraduate and graduate students in their research, actively seek extramural funding, and contribute to the vibrant curriculum of the department at both the undergraduate and graduate (Master’s) levels. In addition to pursuing an outstanding research program, the successful candidate will be expected to provide effective instruction and advising to a diverse population of undergraduate and graduate students. The candidate will teach an undergraduate genetics course and courses in their specialty. We seek candidates whose research, teaching and/or service has prepared them to contribute to our department’s commitment to Diversity, Equity, and Inclusion. Applicants should have a Ph.D. and post-doctoral experience. Review of applications will begin 2 September 2022 and will continue until position filled.

https://jobs.sciencecareers.org/job/610225/geneticist/

https://jobs.villanova.edu/

Contact: Troy Shirangi, Ph.D. troy.shirangi@villanova.edu

The Boston College Biology Department is recruiting a tenure-track faculty member (open rank) with research and teaching interests in Developmental Biology. Candidates whose research programs synergize with department research interests in regeneration or organismal/evolutionary development will be given special consideration. The Biology Department is unified by common interests in answering fundamental biological questions, a commitment to undergraduate education, and mentorship of graduate students in the Biology PhD Program. In alignment with the University’s commitment to building a culturally diverse, equitable and inclusive academic community, we seek applicants who are committed to the advancement of historically underrepresented and marginalized communities in the sciences.
Please find more information here: https://apply.interfolio.com/114124

We seek to recruit an outstanding scientist performing basic research in any area of biology, to fill a tenure-track faculty position at Boston Children’s Hospital and Harvard Medical School. Particular emphasis will be placed on applicants who have not yet established an independent research group. The applicant is expected to establish a leading research laboratory in the Gastroenterology Division at Boston Children’s Hospital, which is situated centrally on Harvard’s Longwood Medical Area Campus. The position comes with a competitive startup package and the opportunity to interface with and train outstanding students that enter Harvard’s graduate, undergraduate and medical programs. Candidates must have a Ph.D., an M.D., or an equivalent graduate degree. Chair of Search Committee: Jonathan Kagan, Ph.D.; Chief, Division of Gastroenterology, Hepatology and Nutrition: Scott B. Snapper, M.D., Ph.D.

For consideration, please send via your e-mail the following requested items to Karen Rodzenko, karen.rodzenko@childrens.harvard.edu .

  1. Cover letter

2. C.V. including a list of publications

3. Research proposal, including prior research accomplishments

4. Three blind letters of recommendation – these will be sent by your references directly to karen.rodzenko@childrens.harvard.

THE APPLICATION DEADLINEIS November 1, 2022.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related condition or any other characteristic protected by law.

Graduate student, PhD position - Cardiac Development


Graduate student positions available in the Bloomekatz lab. Our research seeks to understand the mechanisms underlying the regulation of morphogenetic and identity transformations that occur during cardiac development and disease. We take an interdisciplinary approach, combining the genetic and imaging strengths of zebrafish (including CRISPR/Cas9, forward screens and time-lapse experiments) with both biophysical and cell biological methodologies. New projects include biomechanics, glycosylation and disease modeling.

If you are interested in joining our lab as a PhD student, please contact us directly at josh@olemiss.edu.

-More information about the laboratory can be found at http://thebloomekatzlaboratory.org.

-Additional positions, including a rotation program, are also available in our interdisciplinary graduate program in the department of Biology at the University of Mississippi. For more information about our graduate program including rotations please see http://biology.olemiss.edu

https://www.jobs.ac.uk/job/CSR746/research-associate

Closing date: 22nd September 2022

Sculpting the labyrinth: epithelial morphogenesis in the developing zebrafish inner ear

Fixed term: 03.10.2022 to 03.10.2025

A Postdoctoral Research Associate position is available in the research group of Professor Tanya Whitfield (www.sheffield.ac.uk/biosciences/people/academic-staff/tanya-whitfield).

The overall aim of the Whitfield lab research programme is to use genetic, molecular and cellular, and imaging/image analysis approaches to understand the development and function of the vertebrate inner ear, the organ of hearing and balance. You will join a small team working on epithelial morphogenesis of the developing semi-circular canal ducts. This fascinating process involves changes in epithelial curvature and cell shape, fusion and perforation of epithelial cell sheets, changes in cell shape involving redistribution of extracellular matrix, cytoskeletal and cell adhesion factors, together with apoptosis. Several different projects are available to suit the interests and skills of the successful candidate. The research programme is generously funded through a Wellcome Trust Investigator Award to Professor Whitfield.

You will be able to make a significant contribution to the ongoing research of the Whitfield lab through the design and execution of experiments along with appropriate data analysis approaches. An essential part of the role is to disseminate findings by writing papers and presenting ongoing work at conferences and seminars. By working alongside PhD students, technical staff, and undergraduate and MSc project students, you will also have opportunities to develop your supervision and teaching skills.

You will work within the Development, Regeneration and Neurophysiology Research Cluster within the School of Biosciences, a supportive and collaborative collective of researchers using model organisms to address biomedical research questions. We have strong links with colleagues across the School and have developed additional collaborative links for this project with labs within the School, elsewhere in the UK and in the US. Numerous opportunities for further training and career development are offered by the University of Sheffield, all within one of the UK’s most livable cities.

Applicants must have a PhD in Developmental Biology or related discipline, or equivalent experience, with a strong motivation for and commitment to research in cell and developmental biology. Prior experience working with zebrafish embryos, with strong experimental skills including zebrafish transgenesis, live imaging and quantitative image analysis approaches, are desirable. The ability to work independently is essential, while maintaining a strong team ethic with excellent communication skills. The post demands a flexible attitude and an ability to respond positively to the challenges faced in the research environment.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

To find out what makes the University of Sheffield a remarkable place to work, watch this short film: http://www.youtube.com/watch?v=7LblLk18zmo , and follow @sheffielduni and @ShefUniJobs on Twitter for more information.

Whitfield lab: https://www.sheffield.ac.uk/biosciences/people/academic-staff/tanya-whitfield
To find out about life in the lab, visit our blog: http://whitfield-lab-news.blogspot.com/
Twitter: @TTWhitfieldLab
For further information, please contact Tanya Whitfield: t.whitfield@sheffield.ac.uk
To apply, please follow the ‘Apply’ link from this page: https://www.jobs.ac.uk/job/CSR746/research-associate

https://www.jobs.ac.uk/job/CSP166/research-technician

Closing date: 15th September 2022

A Research Technician position is available in the research group of Professor Tanya Whitfield (www.sheffield.ac.uk/biosciences/people/academic-staff/tanya-whitfield).

The overall aim of the Whitfield lab research programme is to use genetic, molecular and cellular approaches to understand the development and function of the vertebrate inner ear, the organ of hearing and balance. Specifically, this post will provide technical support and assistance for a Wellcome-Trust-funded project on the development of the semi-circular canal system, using the zebrafish as a model system. The work will involve routine laboratory support together with the opportunity to contribute to one or more specific research projects. In addition, the successful candidate will help to provide support and supervision for undergraduate and Masters-level project students in the lab. The post demands a flexible attitude and an ability to respond positively to the challenges faced in the research environment.

Applicants must hold a good honours degree or equivalent in a related biological discipline or equivalent experience, along with enthusiasm and interest in developmental biology and genetics. Experience in molecular biology, including subcloning, sequence analysis and genomics, is essential. In addition, you will be motivated and committed to contributing to scientific research. Excellent interpersonal skills and the ability to work with other members of the research team are essential.

We’re one of the best not-for-profit organisations to work for in the UK. The University’s Total Reward Package includes a competitive salary, a generous Pension Scheme and annual leave entitlement, as well as access to a range of learning and development courses to support your personal and professional development.

We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

To find out what makes the University of Sheffield a remarkable place to work, watch this short film: http://www.youtube.com/watch?v=7LblLk18zmo , and follow @sheffielduni and @ShefUniJobs on Twitter for more information.

To find out about life in the lab, visit our blog: http://whitfield-lab-news.blogspot.com/

Twitter: @TTWhitfieldLab
For further information, please contact Tanya Whitfield: t.whitfield@sheffield.ac.uk
To apply, please follow the ‘Apply’ link from this page: https://www.jobs.ac.uk/job/CSP166/research-technician