Blog from June, 2021

The Sokol laboratory at the Icahn School of Medicine at Mount Sinai, New York, is looking for a research fellow to join our group in the fall of 2021. Our laboratory is in the Department of Cell, Developmental and Regenerative Biology, with a number of groups with highly collaborative, developmental and stem cell biology program. Besides high-quality research core facilities, career guidance and professional development training are provided for postdoctoral fellows.

Our group studies how embryonic signaling pathways control cell polarity and cell movements during gastrulation and neural tissue development. A successful candidate will use live cell imaging and genomic/proteomic approaches to study how signaling molecules and mechanical forces regulate collective cell behaviors in early  Xenopus  and zebrafish embryos. Read more at http://labs.icahn.mssm.edu/sokollab/  and in in our recent papers.

Preference will be given to recent graduates with strong background in cell biology, biochemistry or genomics/bioinformatics.  Salary will be commensurate with experience. Potential candidates may send their CV, a short description of relevant expertise and research interests, list of publications and the names of three references to Dr. Sergei Sokol (sergei.sokol@mssm.edu).

 

The Scientific Project Manager is a non-tenure track position at Yale University within the Zebrafish Phenotypic Core for Precision Medicine (established 2019). The Project Manager will provide support and/or assistance to ensure successful experiments by Yale and non-Yale Investigators using zebrafish models in their research programs. An independent research space will be provided with a fully equipped and managed zebrafish facility. 

The Core offers both “assisted” services, i.e., Project Manager leads the project for the Investigator, and “unassisted” services, i.e., Project Manager assists Investigators who have experience with zebrafish models with their projects. The candidate will work within a team on a dedicated portfolio of their own research projects.

Major Responsibilities

  • Project Management

  • Proficiency in designing and leading scientific projects, including project scope, study design, implementing the experimental plan/protocol, troubleshooting, and data analysis/reporting

  • Identify issues and work with and/or assist team member(s) to resolve issues affecting project scope, quality, effort, risk and timelines

  • Strong managerial skills, including mentoring less experienced Investigators, coordinating personal efforts, ensuring quality work, ensuring all required compliance requirements and standards are maintained, and meeting project deadlines, all with the goal of minimizing experimental failures and achieving timely project completion with strong scientific outcomes

  • Communicate effectively zebrafish techniques and biology to researchers and clinicians not expert in the field.

  • “Assist” Services: Conduct a study for an Investigator, starting with assistance from study design through data analysis/reporting

  • Coordinate and be accountable for multiple tasks and/or projects in progress simultaneously

  • Ability to work independently and with multidisciplinary teams

  • Participate in regularly scheduled project team meetings

  • Maintain appropriate and required financial records and generate reports as requested

  • Participate in the Core’s ongoing development, including marketing of services, proposals for Core improvements, and staying abreast of technical and scientific advancements in the zebrafish field

Qualifications

  • PhD and postdoctoral experience in a scientific field(s) related to zebrafish biology

  • First author publications related to zebrafish projects are preferred

  • Excellent technical skills, including maintenance of zebrafish colonies, phenotypic analysis of zebrafish embryos and/or adults, microscopy (conventional confocal, two photon or light sheets analysis), gene editing strategies (transgenesis, gene knockin-knockout).

  • Strong interpersonal skills

  • Excellent organizational and multi-tasking skills as needed to perform responsibilities listed above

  • Excellent written and verbal skills

Application procedure

Please send your CV plus the name of three references to: andrew.e.prendergast@yale.edu and cc: stefania.nicoli@yale.edu with subject heading “YZPC Position”



A postdoctoral position is available in the laboratory of Dr. Saulius Sumanas at the University of South Florida in Tampa, FL. Sumanas lab uses zebrafish to study molecular mechanisms of vascular development and disease. The lab has recently relocated to USF Health Heart Institute, which is a state-of-the art facility focused on cardiovascular research and located next to the waterfront and Tampa downtown. More information about our research is available at:

https://health.usf.edu/medicine/labs/sumanas-lab/

Applicants must have (or expect to have shortly) Ph.D. in a biology related field. Experience in developmental, molecular and / or vascular biology areas is highly prefered. Zebrafish experience is not necessary. Please e-mail your CV to: ssumanas@usf.edu


A fully funded postdoctoral position is available to study vascular development, angiogenesis, and lymphangiogenesis in the zebrafish in the laboratory of Dr. Brant Weinstein in the NICHD Division of Developmental Biology (DDB) in Bethesda, Maryland. 

The Weinstein laboratory uses a variety of molecular, cellular, genetic, transgenic, microscopic imaging, and next-gen sequencing approaches to study the specification, patterning, and differentiation of developing blood and lymphatic vessels.  Some of our current areas of research interest include endothelial specification and differentiation, assembly of vascular networks and the cues that guide their patterning; morphogenesis of vascular tubes, regulation of vascular integrity, and isolation and molecular characterization of novel vascular-specific mutants. The scientific environment, resources, and stipend support for this position are superb. Learn more about our current research.


Interested applicants should have a Ph.D. or M.D. and less than 3 years' postdoctoral experience. To apply, send a curriculum vitae, bibliography, cover letter with a brief description of research experience and interests, and the names of 3 references (with phone numbers) via e-mail to weinsteb@mail.nih.gov and to amy.parkhurst@nih.gov.


The NIH is dedicated to building a diverse community in its training and employment programs.

Postdoctoral Position in the Epigenetics of Development at the National Institutes of Health
in Bethesda, Maryland


A fully funded postdoctoral position is available to study epigenetics of development using
zebrafish as well as cavefish, mouse, and cell culture models in the laboratory of Dr. Brant
Weinstein in the NICHD Division of Developmental Biology (DDB) in Bethesda, Maryland. The
Weinstein laboratory uses a variety of cutting-edge molecular, cellular, genetic, transgenic,
microscopic imaging, and next-gen sequencing approaches to study the role of epigenetics
during development. In addition to other related studies, the laboratory is currently carrying
out the first-ever genetic screen for vertebrate tissue-specific epigenetic regulatory genes using
a novel "EpiTag" transgenic epigenetic reporter line. The scientific environment, resources, and
stipend support for this position are superb. Learn more about research in the Weinstein lab.


Interested applicants should have a Ph.D. or M.D. and less than 3 years' postdoctoral
experience. To apply, send a curriculum vitae, bibliography, cover letter with a brief description
of research experience and interests, and the names of 3 references (with phone numbers) via
e-mail to weinsteb@mail.nih.gov and to amy.parkhurst@nih.gov.


The NIH is dedicated to building a diverse community in its training and employment programs.

A laboratory/aquatics technician is sought for a zebrafish research laboratory at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) at the NIH.  The successful applicant will work with researchers in the laboratory of Dr. Brant Weinstein in the NICHD Division of Developmental Biology (DDB) in Bethesda, Maryland.  The Weinstein laboratory uses a variety of molecular, cellular, genetic, transgenic, microscopic imaging, and next-gen sequencing approaches to study the specification, patterning, and differentiation of developing blood and lymphatic vessels, the meninges and the neurovascular interface, and developmental epigenetics.  To learn more about the Weinstein laboratory see https://www.nichd.nih.gov/research/atNICHD/Investigators/weinstein  

Qualifications:

Applicants must possess a B.S. in Biological Sciences and 3 years experience in a laboratory research environment including basic molecular biology tasks. Aquatic species experience in a research setting is desirable.

 

Description:

Provide technical research services, working in partnership with research staff members in their conduct of biomedical research.  Provide basic molecular biology assistance including tasks such as bacterial culture and transformation, DNA purification, PCR, gel electrophoresis, RNA extraction, reverse transcription, in situ hybridization, antibody staining, SDS-page gel running, and Western blotting.  Also provide some general husbandry and management support for a zebrafish research colony, as well as more specialized support such as in vitro fertilization, fin clipping, and microinjection of zebrafish eggs.  

 

To apply email a cover letter and full resume with names and contact information for three references to Brant Weinstein to weinsteb@mail.nih.gov

 

Must be a US Citizen or currently hold authorization to work in the US.

Res Post Doc Fellow -Mitochondrial Medicine

Philadelphia, PA, US, 19104

Location: LOC_ABRAMSON-Abramson Building 

Req ID: 117165

Shift: Any

Employment Status: Regular - Full Time 

Job Summary

Mitochondrial Medicine, a Frontier Program at Children’s Hospital of Philadelphia (CHOP), is excited to offer a postdoctoral fellow position

Mitochondrial Medicine at Children’s Hospital of Philadelphia (CHOP) is emerging as the premiere center in the world for multidisciplinary clinical care, advanced diagnostics and therapies, and individualized basic, translational, and clinical research programs dedicated to improving the health of patients of all ages living with mitochondrial disease. The program is part of the Division of Human Genetics.

Mitochondrial Medicine is designated a Frontier Program by CHOP. Frontier Programs are unique, cutting-edge programs that will forge important new discoveries, deliver novel therapies, and help even more children and adults thrive.

Under the direction/guidance of a mentor (principal investigator), assume responsibility for a specific, on-going research project.  The postdoc experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.  Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. Postdocs will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings.  Postdoctoral fellows also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

Dr. Marni Falk’s research laboratory at The Children’s Hospital of Philadelphia Research Institute was established in 2006 and is focused in researching the mechanisms underlying disease, and potential novel therapies, for mitochondrial respiratory chain diseases. The laboratory primarily uses human cell, C. elegans (worm) and zebrafish small animal models, and occasionally mouse models for these purposes.

We have a position open immediately for a research technician to join the group to investigate the therapeutic mechanisms of primary mitochondrial disease through whole-animal behavioral phenotyping and mitochondrial physiology studies, as well as assisting in the evaluation of the efficacy and toxicity of pharmacologic agents in both cell and animal models of primary mitochondrial respiratory chain diseases.  This work involves analyses of candidate therapies and high-throughput drug screening, with both academic and pharma partners.     

 

Job Responsibilities

  1. Conduct independent scholarly research and develop new methods and protocols

  2. Participate in project planning, recording and evaluation of data

  3. Acquire technical, lab management and grant writing skills

  4. Participate in seminars, lectures, poster sessions and presentation at national meetings

  5. Supervise junior lab members

  6. Assist with other research projects

Required Licenses, Certifications, Registrations

Required Education and Experience

  • A terminal degree PhD, MD, DVM, etc.

  • According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

https://urldefense.com/v3/__https://career4.successfactors.com/sfcareer/jobreqcareer?jobId=117165&company=C0000169453P__;!!C5qS4YX3!T5v06m6XHE3F9QVMQvZAjzcTV3tw7JUMl8Oo-_pAFJlASXrzwTB32TgpexHvoyKp8bM$

The Max Planck Institute for Brain Research (MPI for Brain Research) in Frankfurt/Main is a vibrant research institution in the field of basic research in Neuroscience with a focus on understanding the functions of the brain’s circuits. The institute is located in a state-of-the-art research building on Campus Riedberg (housing approx. 300 employees) with modern labs, animal husbandry and support facilities (http://www.brain.mpg.de ).

Our researchers from many different backgrounds (e.g., molecular biology, genetics, electrophysiology, imaging, behavior, physics, computer science and mathematics) collaborate in an interactive and integrative environment to investigate the structure and function of neuronal networks.

The Schuman Lab (Department of Synaptic Plasticity) is looking for (a)

Postdoctoral Fellow(s) (m/f/div)

to examine the neural substrates of learning, memory and social behavior at the synaptic and network level using zebrafish (e.g. Anneser et al., Nature, 2020; https://doi.org/10.1038/s41586-020-2988-z ).

Your profile:

The ideal candidate has a Ph.D. and is an independent and creative thinker with a strong work ethic and significant experience using zebrafish and molecular biology, imaging and/or behavioral testing. This position is a unique opportunity to work in a highly interdisciplinary environment that is equipped with a new, state-of-the-art fish facility, as well as ample imaging and electrophysiology resources.

We offer:

An attractive environment in a pleasant, friendly working atmosphere with an excellent infrastructure

Employment with all benefits of the public service

Continuing education and training

Company pension plan

Family service (baby and children's room at the institute, day care center on campus)

Company health management (e.g. company doctor, sports offers)

Cafeteria / bistro in the institute

Good connections to public transportation

Free parking on the institute’s premises

Compensation is in accordance with the TVöD (German public service) salary scale. Social benefits correspond to those of the public service.

The Max Planck Society is an equal opportunity employer and is striving to increase the proportion of women in areas where they are under-represented. It therefore expressly encourages female applicants. The Max Planck Society is striving to employ more individuals with disabilities. It therefore expressly encourages applicants with disabilities.

The compatibility of work and family is very important to us; we offer the possibility of childcare in the kindergarten Kairos close to our institute. Further information can be found on our homepage: http://www.brain.mpg.de .

Please send your application electronically as a single pdf document including a concise statement of research interest, CV, and contact information for three letters of reference to anita.kulak@brain.mpg.de

 

Erin M. Schuman, Ph.D.

http://brain.mpg.de/research/schuman-department.html

 

POSTDOCTORAL POSITION in TOXICOLOGY in the lab of Jeff Yoder at North Carolina State University (https://jeffyoderlab.wordpress.ncsu.edu/ ).

Conduct research in the field of toxicology using new automated microscopy systems. Work with zebrafish embryos and human cell culture. Study the impact of multiple PFAS on development and immune function .  

Duties & Responsibilities:

Execute laboratory experiments in toxicology and immunotoxicology using in vivo (zebrafish) and in vitro (human cell culture) models. Organize and execute toxicology-based experiments to evaluate computer automated in vivo imaging of zebrafish embryos to manual imaging of embryos. Organize and execute immunotoxicology-based experiments to evaluate the impact of PFAS exposure on zebrafish embryos and human cell lines. Maintain multiple zebrafish lines and human cell culture lines. Supervise undergraduate student researchers.

For more information and to apply go to https://jobs.ncsu.edu/postings/144836  

The MDI Biological Laboratory is a rapidly growing, independent, non-profit biomedical research institution. Its mission is to improve human health and well-being through basic research, education, and development ventures that transform discoveries into cures.

In 2013, the MDI Biological Laboratory was recognized by the National Institutes of Health as a Center of Biomedical Research Excellence (COBRE) for its innovative research program in regenerative and aging biology and medicine. The Institution’s expert, interdisciplinary faculty utilizes multiple genetically tractable model organisms and diverse cell systems to define mechanisms of tissue repair and regeneration and characterize changes that occur in cells and tissues with disease and aging.

Job Summary

We are currently accepting applications for a Post-doctoral research fellow in the Haller laboratory (email hhaller@mdibl.org) with an anticipated start date in September, 2021. Our research focuses on understanding microvascular disease and endothelial cell function in the kidney. We investigate mechanisms of renal regeneration and vascularization. We use the zebrafish as a model organism and renal IPS-cell derived organoids to study the molecular and cellular mechanisms of retinal and olfactory neurons regeneration.  Recently, we have started to work with turquoise African killifish ATK to understand the microvasculature and endothelial cell differentiation during aging. 

Our laboratory in the Kathryn W. Davis Center for Regenerative Biology and Aging employs a range of imaging and molecular technologies including confocal microscopy, live imaging, transgenesis, CRISPR-genome engineering and single cell RNA sequencing to study the biological mechanisms underlying endothelial  cell reprogramming in vivo. We are seeking a highly motivated postdoctoral researcher with a strong background in developmental biology and/or physiology, or related field. The successful candidate will be expected to conduct research using cellular and molecular biological techniques to characterize the mechanisms regulating endothelial cell differentiation in disease and regeneration.

The collaborative research environment at the MDIBL offers an excellent opportunity for career development. Funding is available for 3 years, with the expectation that the candidate will work with Dr. Haller to apply for fellowships during this time. The MDIBL offers a benefits package and competitive salary.

Minimum Qualifications

Ph.D. in a biological science or other relevant area and prior publication of original research articles in peer-reviewed journals.

Preferred Qualifications

Experience with basic cell and molecular biology techniques.

Experience with advanced microscopy

Experience with single cell RNA sequencing experiments and biological datasets analysis.

Applicants should have the ability to interpret data, summarize findings, and work independently and collaboratively to synthesize new ideas to develop their project(s).

Application process      

Please include:

  1. a letter of intent outlining special interest in the position, overall related qualifications and experience and career goals.

  2. curriculum vitae

  3. the names and contact information of three professional references

Interested applicants should apply at www.mdibl.org/careers.

 

 

 

 

RESEARCH TECHNICIAN II – John Rawls Lab and Duke University School of Medicine Zebrafish Core Facilities (Z-Core)

Location:  Durham, NC, US, 27710 

 

To apply for this position, please go here: https://careers.duke.edu/job/Durham-RESEARCH-TECHNICIAN-II-NC-27710/748792300/?locale=en_US

 

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe.

 

The Department of Molecular Genetics and Microbiology at Duke University School of Medicine is seeking a research technician with near-immediate availability. The position will be for one year to start with extensions contingent on availability of funding, performance, and needs of the lab.

This position will involve performing a variety of technical and research duties to support the laboratory of Dr. John Rawls (https://sites.duke.edu/rawlslab/ ) and the Duke University School of Medicine Zebrafish Core Facility (Z-Core)(http://sites.duke.edu/zebrafishfacility/ ). Dr. Rawls’ lab uses zebrafish, mice, and other platforms to investigate mechanisms of host-microbiome interactions in the intestine, and their implications for digestive physiology, nutrition, metabolism, inflammation, and inter-organ communication. Z-Core is a multi-site shared resource that offers aquaculture services to a diverse group of biomedical researchers at Duke University School of Medicine using zebrafish and stickleback as a model organisms.

 

Description of Research Activities:

 

The successful candidate will have the demonstrated ability to perform, or be willing to learn, the following tasks in a research laboratory:

 

  1. Technical duties conducted routinely in a vertebrate animal physiology laboratory such as molecular cloning, DNA and RNA extraction, genotyping, microscopy, imaging, microinjection, animal handling and manipulation. The candidate will be expected to document procedures and collect data in an organized, complete, and accurate fashion.

 

  1. Laboratory maintenance duties including the preparation of culture media, chemicals, reagents and solutions, as well as assisting with maintaining equipment and lab reagent inventories.

 

  1. Support duties include assisting faculty, postdocs, students, and staff in the development and execution of new research procedures and techniques. This would include providing support for zebrafish and mouse experiments.

 

The successful candidate will also have the demonstrated ability to perform, or be willing to learn, the following tasks in a zebrafish aquaculture facility:

 

  1. Daily zebrafish care and maintenance duties include providing fish feedings, caring for Artemia cultures, checking fish health daily, transferring embryos and providing care to nursery racks.

 

  1. Daily zebrafish facility maintenance duties include recording water parameters and reviewing for abnormal readings, changing system filters, cleaning, maintenance, and organization of tanks and aquaculture components, assisting facility management in resolving any problems in facility operation, supporting facility sanitation protocols, and assisting in writing and maintaining compliance with IACUC protocols. Occasional weekend hours may be required.

 

  1. Communicate effectively with of zebrafish facility staff as well as facility users, including explaining and enforcing animal care guidelines and protocols.

 

Required Qualifications: Education/Training: Minimum of a Bachelor’s degree in marine biology, aquaculture, zoology, biology, botany, or other related fields. Experience: Previous laboratory experience is preferred but not required. Demonstrated ability to work effectively in a team and individually is also preferred but not required. Individuals with zebrafish or other aquaculture experience will be given priority, and candidates with relevant experience in rodent or other animal models are also encouraged to apply.

 

Minimum Qualifications:

Education: Work generally requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.

Experience:  None required above education/training requirement. 

 

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

 

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

 

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

 

To apply for this position, please go here: https://careers.duke.edu/job/Durham-RESEARCH-TECHNICIAN-II-NC-27710/748792300/?locale=en_US

 
Nearest Major Market: Durham
Nearest Secondary Market: Raleigh

Requisition Number:  122029

Biotechnical customer support

Gene Tools, LLC is an established biotech company of 15 employees in the mid- Willamette valley of Western Oregon. Gene Tools produces and markets Morpholino oligos for antisense applications worldwide. We are seeking a Ph.D. biologist for technical customer support, marketing, transaction support and business development. Gene Tools manufactures Morpholino oligos to alter expression of targeted genes. The candidate needs a good molecular biology and gene regulation background ideally with experience using Morpholino oligos, model organisms (e.g. zebrafish, Xenopus, urchin, etc.), microinjection, nucleotide databases, biological & organic chemistry, graphic arts, and technical writing. Key daily tasks will be selection of optimal Morpholino sequences and technical discussions with customers by telephone and email. Expect work in a small team, helping to solve unexpected challenges. The position will involve some travel for exhibiting at conferences and trade shows. Medical and dental plans are available; profit share paid after two years of full-time employment; employer contributes 2% of salary to retirement plan.

Gene Tools is located in a 20,000 sq. ft. manufacturing/research facility in a rural setting not far from the campus of Oregon State University. Gene Tools, LLC, established in 1997, is a small, family-owned and operated, privately-held biotech company. Because we are a small company, employees have the opportunity to do many different tasks and are relatively self-directed.

To apply, send cover and CV or resume to:
Dr. Jon Moulton, Biology/Special Projects/Customer Support jmoulton@gene-tools.com

A Postdoctoral Fellow position is available in the Schilling lab in the Department of Developmental and Cell Biology, University of California, Irvine (https://www.tschilling.bio.uci.edu/ ) to study the genetic mechanisms that coordinate cell migration and cell fate determination during the embryonic development of neural crest cells in zebrafish.

We are interested in how highly migratory cells such as neural crest cells in vertebrate embryos acquire diverse fates such as cartilage, bone, neurons, glia or pigment cells. To address this issue, we take a very multi-disciplinary approach including transcriptomic/bioinformatics analyses, genome editing, zebrafish mutants/transgenics and computational modeling to dissect neural crest cell heterogeneity. We also study gene function using zebrafish mutants, many of which are models for human neural crest-related disorders including craniofacial birth defects, such as cleft palate.

We seek a highly motivated and career-oriented candidate with research expertise in developmental and/or cell biology and molecular genetics, preferably with some experience in bioinformatic analysis. We prefer candidates within a year before or after their graduation with a PhD. A track record of excellent first author publication(s) is required. The salary and benefits will follow NIH standards.

To apply, one should submit their curriculum vitae and the contact information via the following recruitment URL: https://recruit.ap.uci.edu/JPF06609 or contact Dr. Schilling directly at tschilli@uci.edu.

The University of California, Irvine is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.

More Infohttps://devcell.bio.uci.edu/faculty/thomas-schilling

APPLICATION REQUIREMENTS

Document requirements

Reference requirements

  • 3-5 required (contact information only)