Postdoctoral position at the Renal Division, University Medical Center Freiburg, Germany
We are inviting applications for a postdoctoral position within the Renal Organogenesis, Pathology and Repair group at the University Medical Center Freiburg, Germany. We are using the zebrafish embryonic kidney, the pronephros, as a model to study kidney development, kidney injury and repair, and human ciliopathies. Current projects focus on zebrafish models of nephronopthisis and acute kidney injury. Nephronopthisis is an autosomal recessive ciliopathy with more than 25 causative genes and one of the most common causes of end stage renal disease in childhood. Acute kidney injury is a sudden failure or damage to the kidney that occurs within a few hours or days, and it can affect up to two thirds of the patients at intensive care units. We use state of the art methods, such as CRISPR/Cas9 gene editing, single cell RNA sequencing, laser-induced cell ablation and confocal live video microscopy to study the mechanisms of disease genesis and progression, as well as to design approaches to ameliorate these human diseases. Our group is strategically situated at the University Medical Center campus with access to confocal microscopy, FACS sorting, bioinformatics and electron microscopy core facilities. The projects will be carried out in a stimulating work environment with scientific collaborations within the Renal Division with groups using mouse, Xenopus and cell culture models, as well as human genetics to study hereditary kidney diseases.
The successful applicant should hold a PhD or MD degree, be highly motivated, organized, and able to work independently. Strong English skills are required. Prior experience with zebrafish or any of the above mentioned methods is an advantage, but not a prerequisite. Salary and benefits are based on the German public servant remuneration grade table (Tarifvertrag für den Öffentlichen Dienst der Länder (TV-L)). Applications including a cover letter, a detailed CV including a publication list and contacts of up to three referees should be sent as soon as possible and by Dec 31th the latest to
Priv.-Doz. Dr. Toma A. Yakulov