Postdoctoral Research Associate, Knight Lab, King’s College London, London, United Kingdom

Open

The Knight group are recruiting a postdoctoral research associate to investigate how ageing affects muscle stem cell function. The post will be based in the Centre for Craniofacial & Regenerative Biology at Guy’s Hospital in the heart of London. Research in the Centre includes developmental biology, biophysics, stem cell biology and tissue engineering in a vibrant, collaborative, and interactive environment.

We are looking for applicants with a PhD in the area of regenerative or cell biology, with strong skills in analysing gene function and regulation. Experience of working with zebrafish or muscle would be beneficial as would skills in analysing transcriptomic data. Candidates should have an excellent research track record, be committed to the project and keen to work in a multidisciplinary team.

Key requirements will involve functional evaluation of candidate ageing modifiers genes and molecules for their roles in regulating cell behaviour in regenerating muscle of zebrafish. Complementary assays using human cells will be used to determine conservation of function in vertebrates and to identify candidate targets for promoting healthy muscle in ageing. Live cell imaging and analysis, gene function analysis, cell culture, use of zebrafish as a model organism, transcriptomics and molecular network modelling are key skills for this project.

We welcome applications from all qualified candidates regardless of background or culture. Research staff training and development is actively supported at King’s through the action plan for the Concordat for Research Staff.

We are looking for candidates to have the following skills and experience:

Essential criteria

• PhD in cell biology, regenerative biology, or relevant subject

• Experience of working with animal models

• Advanced microscopy and image analysis skills

• Advanced molecular biology and gene manipulation skills

• Highly motivated with interest in subject area and evidence of generating research outputs

• Excellent interpersonal skills, ability to work in teams and have a positive approach to co-operative working

• Excellent scientific writing and presentation skills, logical and consistent record keeping and data analysis skills

• Willingness to mentor and train other team members, to contribute to common group activities and meetings and help as needed

Desirable criteria

1. Experience in analysing gene expression datasets and using computer models for predicting molecular interactions

2. Experience of working in the area of regenerative biology

3. Experience of performing gene manipulation in zebrafish

4. Experience of cell culture

5. Understanding of the ageing field

Key benefits include:

Salary: £43,205 - £45,521 including London Weighting Allowance.

Access to 10 days training and development per annum.

More detail about benefits of working at King’s can be found here:

https://www.kcl.ac.uk/jobs/kings-benefits

Please see details for applying to the post here:

https://www.kcl.ac.uk/jobs/093608-postdoctoral-research-associate

Note the Job id is 093608 and closing date is Sep 1st.

Contact robert.knight@kcl.ac.uk if you have questions about the post.