Postdoctoral Position, Xu lab, Mayo Clinic, Rochester, MN
- Wei-Chia Tseng
A post-doctoral fellow position is available in the laboratory of Dr. Xiaolei Xu, Professor of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine. The successful applicant will join a team that is leveraging powerful zebrafish genetics to model human cardiovascular diseases and polycystic kidney diseases, to decipher underlying mechanisms, and to develop new therapies. The lab recently integrated African Turquois Killifish as a new animal model for studying normative cardiac and kidney aging. Below please find two representative manuscripts from the lab on doxorubicin-induced cardiotoxicity. Applications are invited from candidates who have a strong background in molecular biology, genetics and/or cardiovascular diseases. Previous experience in animal models of human diseases and/or bioinformatics are favored, but not required. Qualified candidates must be self-motivated and have a strong commitment to basic research. Further enquires (enclosing a CV) regarding the scope and detail of the project should be addressed to: xu.xiaolei@mayo.edu or visit https://www.mayo.edu/research/labs/zebrafish-genetics
Ma X, Zhu P, Ding Y, Zhang H, Qiu Q, Dvornikov AV, Kim M, Wang Y, Lowerison M, Herrmann J, Ekker S, Hsiai TK, Lin X and Xu X. (2020) Retinoid X receptor alpha is a spatiotemporally-specific therapeutic target for doxorubicin-induced cardiomyopathy in adult zebrafish._
_Science Advances 6(5), eaay2939, PMID: 32064346.[]Wang Y, Lu X, Wang X, Qiu Q, Zhu P, Ma L, Ma X, Herrmann J, Lin X, Wang W, Xu X. (2021) atg7-Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity. Circ Res. Aug 13. PMID: 34384247.
Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life. Mayo Clinic offers a variety of employee benefits. For additional information please visit Mayo Clinic Benefits.
The following is required for completeness of application:
Current curriculum vitae with bibliography
Proof of doctoral degree (copy of diploma or final transcript with English translation, if applicable) or a letter from your university's Registrar office indicating you have fulfilled all doctoral program requirements and are eligible to graduate.
Please also be prepared that you may be asked to provide three letters of recommendation to the hiring PI prior to an interview. Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program.